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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Retraction of publications is an increasing problem in science and one of the most troublesome issues for biomedical journals&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#8211;3</span></a> The impact of retraction is negative whether it is due to misconduct or not&#44; and it is believed that fraud is more frequent than assumed&#46;<a class="elsevierStyleCrossRefs" href="#bib0165"><span class="elsevierStyleSup">4&#44;5</span></a> Retracted publications usually cause lack of trust in medical science and may affect the credibility of scientific journals&#44; even in the case that some journals are proactive in retraction policies&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Detection of plagiarism has become a concern for editors&#44; and measures such as the implementation of plagiarism detection software have been taken&#46;<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">6&#8211;8</span></a> The literature regarding the use of surveillance tools to detect plagiarism and its results is scarce&#46; In fact we have not found any paper analyzing the use of such tools comparing biomedical journals&#8217; characteristics such as the impact factor&#46; The use of these tools has increased plagiarism detection&#44; but these detected manuscripts do not become public&#44; as when detected during the editorial process authors are warned and therefore the manuscript is not formally retracted because it is directly rejected&#46; Therefore&#44; the increase in retractions due to plagiarism is a result of the manuscripts that have escaped from the journals detection system&#44; which are now increasingly used by high-impact journals&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">9</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Literature focusing on misconduct has been centered more on authors instead of journal&#39;s characteristics<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;10&#8211;15</span></a> involved in retraction or misconduct&#46; Misconduct rates by journal type do not necessarily mean a weak peer-review policy by a specific journal but a high ethical standard or a higher surveillance or sensitivity on claims of what a particular journal has published&#46; The surveillance of what is published is expected to be higher in a high impact journal&#46; We aimed to describe the journal characteristics&#44; mainly the impact factor and journal categories&#44; involved in the retraction process to have a better picture of retraction frequency&#44; particularly that related with misconduct&#46; This paper is part of a previously published study&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> and is exploiting additional information from the same database&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Method</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Search strategy</span><p id="par0020" class="elsevierStylePara elsevierViewall">A PubMed search was conducted looking for articles indexed by PubMed and labeled as retracted publications from January 1<span class="elsevierStyleSup">st</span>&#44; 2013 to December 31<span class="elsevierStyleSup">st</span>&#44; 2016&#46; PubMed is the most used database in biomedical journals and practically all biomedical journals with an impact factor &#40;IF&#41; are indexed there&#46; In fact&#44; other research papers similar to the present one have previously chosen only PubMed as the source to evaluate retractions&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;10&#44;11&#44;14&#44;16&#8211;18</span></a> As previously described&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> the search strategy was the following&#58; &#40;&#8220;retracted publication&#8221;&#91;Publication Type&#93; OR &#8220;retracted publication&#8221;&#91;All Fields&#93;&#41; AND &#40;&#8220;2013&#47;01&#47;01&#8221;&#91;PDAT&#93;&#58; &#8220;2016&#47;12&#47;31&#8221;&#91;PDAT&#93;&#41;&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Data extraction</span><p id="par0025" class="elsevierStylePara elsevierViewall">For each retracted article identified&#44; title&#44; author&#47;s&#44; journal name&#44; date of publication and date of retraction were obtained&#46; The time to retraction was calculated as time elapsed between both dates&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Web of Science was used to determine the Journal Citation Report &#40;JCR&#41; category&#44; 5-year impact factor &#40;5-IF&#41; and the quartile in the category&#46; Impact factor from year of publication or nearest year available was reflected&#46; Journals without 5-IF were left blank&#46; The subject category and&#44; if documented&#44; the contact information for the corresponding author&#39;s institution were recorded&#46; For journals belonging to more than one category&#44; the one corresponding to the highest quartile was selected&#46; In the case of a tie&#44; the first category in order of appearance was considered&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Definition of cause of retraction</span><p id="par0035" class="elsevierStylePara elsevierViewall">Retracted publications were classified based on retraction notice narrative and on the categories proposed by the Committee of Publishing Ethics definitions and previous classifications&#44;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">19</span></a> and were the same as in a previous paper&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> Nine main categories were used&#58; aspects related with data&#44; authors issues&#44; plagiarism&#44; unethical research&#44; journal issues&#44; review process&#44; conflict of interest&#44; other&#44; and unknown&#46;<a class="elsevierStyleCrossRefs" href="#bib0165"><span class="elsevierStyleSup">4&#44;19</span></a> These categories were further classified as misconduct &#40;fraud&#41;&#44; suspicion of misconduct and no misconduct suspicion&#46; Reason for retraction was manually identified from the retraction note&#46; If more than one reason was present&#44; reason was assigned hierarchically&#44; such that manuscripts were assigned to the first reason in the list&#46; Data collection and classification were performed by ICV&#44; and doubtful assignments were discussed with ARR&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Data preparation and analysis</span><p id="par0040" class="elsevierStylePara elsevierViewall">The percentages of total retracted publications and misconduct per 10&#44;000 PubMed registries over time were calculated by dividing the total number of retracted publications due to misconduct by the total number of registries in PubMed for the study period&#46; Quartile category was categorized as high quartile &#40;quartiles 1 and 2&#41; and low quartile &#40;quartiles 3 and 4&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Differences between categorical variables were assessed by Chi-square test or Fisher&#39;s exact test&#46; Continuous variables were compared using Mann-Whitney test&#46; Non-parametric trend test analysis of variance by ranks was used to test for differences over time&#46; STATA&#47;SE&#174; v13 &#40;College Station&#44; Texas&#41; was used for all statistical analyses&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Results</span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Ratio of retraction&#44; journal quartile and JCR categories of retracted articles</span><p id="par0050" class="elsevierStylePara elsevierViewall">For the study period&#44; the total number of retracted publications was 1&#44;082 out of a total of 4&#44;384&#44;945&#44; representing a proportion of 2&#46;5 per 10&#44;000 publications&#46; Six hundred and eleven different biomedical journals retracted papers&#46; The distribution by quartile is shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; Median 5-IF was 2&#46;63 &#40;interquartile range &#91;IQR&#93;&#58; 1&#46;74-4&#46;24&#41;&#46; Of the retracted papers&#44; 51&#46;4&#37; were published in high quartile journals&#44; 33&#46;1&#37; in low quartile journals&#44; and 15&#46;5&#37; were published in journals without IF &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46; Retracted papers were mainly of the biochemistry and molecular biology areas &#40;9&#46;9&#37;&#41;&#44; followed by oncology &#40;7&#46;1&#37;&#41; &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Annual evolution&#44; median time to retraction and reasons for retraction</span><p id="par0055" class="elsevierStylePara elsevierViewall">Despite no significant trend was detected &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;9&#41;&#44; the crude number of retractions has increased over time&#44; with 70 retractions &#40;6&#46;4&#37;&#41; in 2013 and 418 &#40;38&#46;6&#37;&#41; in 2016&#46; Plagiarism has steadily increased with only 35 papers retracted for that reason in 2013 &#40;9&#46;9&#37;&#41; and 161 in 2016 &#40;45&#46;5&#37;&#41;&#46; Plagiarism was also the main cause of retraction in 2016&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">Median time to retraction was 10&#46;0 months &#40;IQR&#58; 5&#46;0-17&#46;0&#41;&#46; Time to retraction was similar between articles published in high and low quartile journals &#40;median time to retraction was of 10&#46;0 months &#91;IQR&#58; 5&#46;0-19&#46;0&#93; for the former and 10&#46;0 months &#91;IQR&#58; 5&#46;0-17&#46;5&#93; for the latter&#41;&#46; There was no difference in time to retraction regarding the specific reason for retraction &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;2&#41;&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Presence of misconduct among retracted papers</span><p id="par0065" class="elsevierStylePara elsevierViewall">Definitive misconduct was found in 707 &#40;65&#46;3&#37;&#41; of all retracted papers&#46; Additionally&#44; proportion of misconduct among retracted papers or reason for retraction did not change over time &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;2&#41;&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Within the retracted publications&#44; among low-impact journals the presence of misconduct was higher with a 73&#37; compared to 61&#37; for the high-impact journals &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">There was a significant trend to a longer time to retraction for papers retracted because of misconduct compared to those papers not retracted due to misconduct &#40;11 months &#91;IQR&#58; 5&#46;9-18&#46;0&#93; vs&#46; 5&#46;9 months &#91;IQR&#58; 2&#46;0-14&#46;0&#93;&#59; p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">There were differences in the percentage of retractions due to misconduct regarding the JCR category&#46; 91&#37; of retracted papers were due to misconduct for pathology journals and 48&#37; for pharmacology and pharmacy journals&#44; &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>&#41;&#46; It can be observed that there are important differences for the burden of misconduct among retracted papers between JCR categories&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">Among the papers retracted because of misconduct&#44; plagiarism was the main reason for retraction&#44; independently of the journal IF &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46; Data manipulation was the second cause of retraction among those papers retracted in high impact journals&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Of all retractions&#44; only 16 &#40;1&#46;5&#37;&#44; all because of misconduct&#41; clearly stated that the journal contacted authors and&#47;or institutions in order to communicate the retraction and the misconduct&#46;</p></span></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Discussion</span><p id="par0095" class="elsevierStylePara elsevierViewall">We present here a description of retractions broken down by journals&#8217; IF&#46; We have found that&#44; of the retracted manuscripts&#44; 51&#46;4&#37; belong to high-impact journals and that it seems that misconduct among retracted papers has apparently a higher presence in low-quartile journals&#46; The most frequent cause of misconduct is plagiarism&#44; accounting for 38&#37; of all retractions in 2016&#46; Finally&#44; only 1&#46;5&#37; of retractions were marked as having triggered an action by journals&#44; a very low percentage&#46; We do not have data on the percentage of journals contacting authors when there is a retraction and if there are differences on the frequency of this contact regarding the journal&#39;s IF&#46; However&#44; and despite no clear data were available&#44; different implications for authors have been previously described following retractions&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">20</span></a> Similarly&#44; some journals decide to penalize authors by preventing them from publishing in the journal for a period of time&#46;<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">8&#44;21</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">Fang et al&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">1</span></a> have shown in a study including papers retracted until 2012 that the mean time to retraction was 32&#46;9 months&#44; which is more than three times longer that the time observed in the present study&#46; We might speculate that this finding served editors to speed up fraud investigation when there is a suspicion and&#44; as a consequence&#44; the time to retraction has been shortened&#46; The same group has also shown that time to retraction because of fraud is longer than when retractions were due to other reasons&#46; This result is in agreement with our finding of a longer time to retraction because of misconduct&#46; This might be related to the difficulty to ensure the facts and to confirm the fraudulent conduct&#46; Also&#44; when retraction is due to reasons other than misconduct&#44; authors might be involved in the process of retraction&#44; and that seems to be a factor related with reduced time to retraction&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Journal IF also has an influence in retraction with a higher proportion of misconduct among retracted papers published in low-impact journals&#46; Previously&#44; the contrary has been shown&#44; suggesting that the greater visibility of high-impact journals promotes higher inspection and a quicker retraction&#46; We have also found that 51&#46;4&#37; of the retracted papers were published in high-quartile journals&#46; It is noteworthy that in high-impact journals&#44; a significant proportion of the misconduct is related to data manipulation by authors&#44; suggesting that high IF might be more attractive as these publications are generally linked to improvements in CVs&#44; grant success&#44; and better job opportunities&#46; This might provide some incentive to commit misconduct to publish in a high-ranking journal even though IF and quantitative measurement of publications has been largely questioned&#46;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">16&#44;22&#44;23</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">Plagiarism accounts for the highest number of retractions for the study period&#46; These data are striking and deserve to be commented given that we have reasons to think that the real number of authors plagiarizing is higher&#46; The use of plagiarism detection software has become more widespread&#46; Despite the fact that the use of these systems prevents having plagiarized published manuscripts&#44; retractions due to plagiarism are increasing by year&#46; It is worth to mention that plagiarism was the main reason for retraction independently of the journal impact&#44; indicating that the implementation of plagiarism detection systems are in great need&#44; independently of the journal&#46; However&#44; these systems have probably prevented finding a significant increase&#46; Hence&#44; and despite awareness of editors&#44; reviewers and readers who undoubtedly are contributing to this increase in detection and retraction&#44; more action has to be done&#46;<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">8&#44;24&#44;25</span></a> However&#44; efforts to limit this phenomenon have to start from the very moment when a manuscript arrives to a medical journal and is assigned to an editor&#46; Detection of plagiarism can be done in three ways&#46; First&#44; detection can rely on the capacity of reviewers and editors to identify previously published papers&#46; Second&#44; it can use plagiarism detection software including that for image fraud detection&#46;<a class="elsevierStyleCrossRefs" href="#bib0265"><span class="elsevierStyleSup">24&#44;25</span></a> And finally&#44; detection can occur when a reader or the author is capable of identifying the plagiarism from an already published paper&#46; This method seems to be the only way to identify plagiarism when the original publication is in a language other than English and is not published in a widely visible journal&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">26</span></a> Actions other than warning authors are needed&#44; such as those in based in education&#46; It has already been tested that warnings against plagiarism are insufficient&#46;<a class="elsevierStyleCrossRefs" href="#bib0280"><span class="elsevierStyleSup">27&#44;28</span></a> There is also a lack of standardization and clarity on retraction management&#44; and databases should provide tools and procedures to trace the retractions and authors committing misconduct&#46;<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">29</span></a></p><p id="par0115" class="elsevierStylePara elsevierViewall">It is worth to mention&#44; that the entire editorial process is not paid&#44; nor valued&#44; and that in general there is not any specific training for the work&#46; Also&#44; the editorial process is based on good faith and goodwill&#46; Consequently&#44; to ask Editors and reviewers an excessive amount of work and to be fully aware of new ways of committing fraud might not be realistic&#46; Some tasks using plagiarism detection using commercial software should be done by biomedical journals&#8217; administrative staff before allowing the manuscript to enter in the editorial process&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Biochemistry and molecular biology and pathology journals are&#44; respectively&#44; the JCR categories with a greater number of retractions&#44; and with the highest proportion of misconduct among retracted papers&#44; though we do not know the total number of published papers within those categories&#46; Despite retractions and misconduct are widespread&#44; this basic discipline accounts for the greater proportion of retractions&#46; Before&#44; non-association was found between a general medicine journal &#40;vs&#46; other&#41; and misconduct&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">13</span></a> In general terms&#44; we believe that the threat of retraction and misconduct is everywhere&#44; and all journals have to be aware of it and implement measures to limit it&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">The main limitation of our study results from the fact that we are only evaluating retractions that have been identified after being published&#44; and we do not address all the plagiarism detected by the journals including any other fraud avoided by early identification during the editorial process affecting rejected papers&#46; Also&#44; as has been previously acknowledged&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> the ability to classify publications as misconduct or not is limited and some data are not accessible&#44; such as quartile of all the publications of the study period&#46; Also&#44; we cannot evaluate the percentage of journals contacting authors and&#47;or institutions when there is a retraction&#44; and if this is related to the journal&#39;s IF&#46; The dynamic nature of data obliges us to be cautious&#46; An additional limitation is that PubMed was the only database consulted to gather the reported data&#44; though we need to take into account the fact that&#44; for medical literature&#44; Medline is the main database&#44; and where the vast majority of journals are indexed&#46; PubMed is also the database where a reader would notice if an article has been retracted&#46; Finally&#44; and perhaps most important&#44; we do not know the total number of papers published in the analysed journals and therefore we cannot infer that the incidence of retractions is higher in low-impact biomedical journals compared to high impact journals&#46; We only can conclude that the crude number of retractions &#40;and also retractions due to misconduct&#41; is higher in low impact journals</p><p id="par0130" class="elsevierStylePara elsevierViewall">To conclude&#44; retraction of scientific publications is associated with both high and low-impact journals&#44; with plagiarism as the main reason of misconduct&#44; independently of the journal IF&#46; It would be recommendable for journals to implement the use of plagiarism detection systems and to standardize measures both before and after the publication of the manuscript&#46; We encourage journal editors detecting misconduct to promote actions beyond those limited to the journal&#46;<elsevierMultimedia ident="tb0005"></elsevierMultimedia></p></span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">Editor in charge</span><p id="par0145" class="elsevierStylePara elsevierViewall">Carlos &#193;lvarez-Dardet&#46;</p></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Transparency declaration</span><p id="par0150" class="elsevierStylePara elsevierViewall">The corresponding author on behalf of the other authors guarantee the accuracy&#44; transparency and honesty of the data and information contained in the study&#44; that no relevant information has been omitted and that all discrepancies between authors have been adequately resolved and described&#46;</p></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0140">Authorship contributions</span><p id="par0155" class="elsevierStylePara elsevierViewall">I&#46; Campos-Varela and A&#46; Ruano-Ravi&#241;a wrote the manuscript and R&#46; Villaverde-Casta&#241;eda critically edited and reviewed the manuscript&#46; All authors provided critical input to the manuscript&#39;s content and have approved the final version&#46; The corresponding author attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted&#46;</p></span><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0145">Funding</span><p id="par0160" class="elsevierStylePara elsevierViewall">None&#46;</p></span><span id="sec0090" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0150">Conflicts of interest</span><p id="par0165" class="elsevierStylePara elsevierViewall">None&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To describe the biomedical journal characteristics that are associated with the retraction of papers&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A descriptive cross-sectional study was conducted&#46; All papers retracted and indexed in PubMed from January 1<span class="elsevierStyleSup">st</span> 2013 to December 31<span class="elsevierStyleSup">st</span>&#44; 2016 were included&#46; We used nine main categories to classify retractions&#58; aspects related with data&#44; authors issues&#44; plagiarism&#44; unethical research&#44; journal issues&#44; review process&#44; conflict of interest&#44; other&#44; and unknown&#46; These categories were further classified as&#58; misconduct&#44; suspicion of misconduct&#44; or no misconduct&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The proportion of retraction was 2&#46;5 per 10&#44;000 publications&#46; Retractions appeared in 611 journals&#46; During the study period&#44; retraction due to misconduct was more frequent among journals with low-impact factor&#46; Within these retracted publications&#44; among low-impact journals the presence of misconduct was higher with a 73&#37; compared to 61&#37; for the high-impact journals &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleMonospace">0</span>&#46;001&#41;&#46; There were differences in the percentage of retractions due to misconduct regarding the journal classification category &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleMonospace">0</span>&#46;001&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Retraction of publications is present in both high- and low-impact factor biomedical journals&#44; but misconduct is more frequent among the papers retracted from lower impact journals&#46; Measures before and after publication should be taken to limit misconduct&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Describir qu&#233; caracter&#237;sticas de las revistas cient&#237;ficas biom&#233;dicas se asocian con la retractaci&#243;n de art&#237;culos&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un estudio transversal en el que se incluyeron todos los art&#237;culos retractados e indexados en PubMed del 1 de enero de 2013 al 31 de diciembre de 2016&#46; Las retractaciones tambi&#233;n se clasificaron de forma m&#225;s detallada&#58; problemas con los datos o manejo de datos&#59; aspectos de autor&#237;a&#59; plagio&#59; investigaci&#243;n no &#233;tica&#59; aspectos relacionados con la revista&#59; problemas con el proceso de revisi&#243;n&#59; conflicto de intereses o razones desconocidas&#46; Posteriormente se clasificaron como mala conducta&#44; sospecha de mala conducta o sin mala conducta&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">La proporci&#243;n de retractaciones fue de 2&#44;5 por cada 10&#46;000 publicaciones&#46; Hubo retractaciones en 611 revistas&#46; Durante el periodo de estudio&#44; la retractaci&#243;n por mala conducta fue m&#225;s frecuente en revistas con bajo factor de impacto&#44; y entre los art&#237;culos retractados&#44; hubo m&#225;s mala conducta &#40;73&#37;&#41; entre las revistas de bajo factor de impacto&#44; en comparaci&#243;n con las revistas con alto factor de impacto &#40;61&#37;&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Tambi&#233;n se observan diferencias en el porcentaje de retractaciones debidas a mala conducta seg&#250;n la categor&#237;a de clasificaci&#243;n del Journal Citation Report &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La retractaci&#243;n de publicaciones est&#225; presente tanto en revistas de alto como de bajo factor de impacto&#44; pero la retractaci&#243;n por mala conducta es m&#225;s habitual en revistas biom&#233;dicas de bajo impacto&#46; Deben tomarse medidas antes y despu&#233;s de la publicaci&#243;n para limitar la mala conducta cient&#237;fica&#46;</p></span>"
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">230 &#40;21&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">239 &#40;22&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">119 &#40;11&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>No impact factor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">168 &#40;15&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2377093.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Distribution of retracted journals by quartile&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Only reported categories with a proportion of retractions greater than 3&#37;&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Retractions&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Biochemistry &#38; Molecular Biology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">107 &#40;9&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Oncology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">77 &#40;7&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mutidisciplinay Sciences&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">62 &#40;5&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medicine&#44; Research &#38; Experimental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45 &#40;4&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pathology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">36 &#40;3&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Biotechnology &#38; Applied Microbiology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">35 &#40;3&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medicine&#44; General &#38; Internal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">33 &#40;3&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pharmacology &#38; Pharmacy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">33 &#40;3&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2377095.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Distribution of retracted journals by Journal Citation Report category&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Included only articles with known quartile&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">High quartile&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Low quartile&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Misconduct</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Yes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">339 &#40;61&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">261 &#40;72&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26 &#40;4&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14 &#40;3&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Uncertain&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">191 &#40;34&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">83 &#40;23&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2377096.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Distribution of misconduct by quartile&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0020"
        "etiqueta" => "Table 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at4"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Misconduct&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pathology&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">33 &#40;91&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medicine&#44; General &#38; Internal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">26 &#40;78&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Oncology&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Medicine&#44; Research &#38; Experimental&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">35 &#40;77&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">24 &#40;68&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">73 &#40;68&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">37 &#40;59&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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          "en" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Presence of misconduct by Journal Citation Report category&#46;</p>"
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          "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">What is known about the topic&#63;</span><p id="par0135" class="elsevierStylePara elsevierViewall">Scientific misconduct is a relevant problem in scientific publication&#46; There is little knowledge on the burden of misconduct within retracted papers by biomedical journals and the misconduct characteristics when it is present&#46; Furthermore&#44; there is scarce information regarding retractions and misconduct broken down by journals&#8217; impact factor and Journal Citation Report categories&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">What does this study add to the literature&#63;</span><p id="par0140" class="elsevierStylePara elsevierViewall">Retraction and misconduct in publications is present in both high- and low-impact factor journals&#44; but misconduct is more frequent among papers retracted in lower impact journals&#46; There are also differences on the presence of misconduct between journal&#39;s classification categories&#46; More in-depth research is needed to know misconduct related differences between journals&#8217; characteristics&#46;</p></span></span>"
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Original article
Retraction of publications: a study of biomedical journals retracting publications based on impact factor and journal category
Retractación de publicaciones: estudio de los artículos de retractación de revistas biomédicas basado en el factor de impacto y la categoría de la revista
Isabel Campos-Varelaa,b, Ramón Villaverde-Castañedac, Alberto Ruano-Raviñac,d,
Corresponding author
alberto.ruano@usc.es

Corresponding author.
a University of Santiago de Compostela (CLINURSID), Santiago de Compostela, Spain
b Department of Internal Medicine, Hospital of Santiago de Compostela, Santiago de Compostela, Spain
c Area of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain
d CIBER de Epidemiología y Salud Pública (CIBERESP), Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Retraction of publications is an increasing problem in science and one of the most troublesome issues for biomedical journals&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#8211;3</span></a> The impact of retraction is negative whether it is due to misconduct or not&#44; and it is believed that fraud is more frequent than assumed&#46;<a class="elsevierStyleCrossRefs" href="#bib0165"><span class="elsevierStyleSup">4&#44;5</span></a> Retracted publications usually cause lack of trust in medical science and may affect the credibility of scientific journals&#44; even in the case that some journals are proactive in retraction policies&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Detection of plagiarism has become a concern for editors&#44; and measures such as the implementation of plagiarism detection software have been taken&#46;<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">6&#8211;8</span></a> The literature regarding the use of surveillance tools to detect plagiarism and its results is scarce&#46; In fact we have not found any paper analyzing the use of such tools comparing biomedical journals&#8217; characteristics such as the impact factor&#46; The use of these tools has increased plagiarism detection&#44; but these detected manuscripts do not become public&#44; as when detected during the editorial process authors are warned and therefore the manuscript is not formally retracted because it is directly rejected&#46; Therefore&#44; the increase in retractions due to plagiarism is a result of the manuscripts that have escaped from the journals detection system&#44; which are now increasingly used by high-impact journals&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">9</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Literature focusing on misconduct has been centered more on authors instead of journal&#39;s characteristics<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;10&#8211;15</span></a> involved in retraction or misconduct&#46; Misconduct rates by journal type do not necessarily mean a weak peer-review policy by a specific journal but a high ethical standard or a higher surveillance or sensitivity on claims of what a particular journal has published&#46; The surveillance of what is published is expected to be higher in a high impact journal&#46; We aimed to describe the journal characteristics&#44; mainly the impact factor and journal categories&#44; involved in the retraction process to have a better picture of retraction frequency&#44; particularly that related with misconduct&#46; This paper is part of a previously published study&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> and is exploiting additional information from the same database&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Method</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Search strategy</span><p id="par0020" class="elsevierStylePara elsevierViewall">A PubMed search was conducted looking for articles indexed by PubMed and labeled as retracted publications from January 1<span class="elsevierStyleSup">st</span>&#44; 2013 to December 31<span class="elsevierStyleSup">st</span>&#44; 2016&#46; PubMed is the most used database in biomedical journals and practically all biomedical journals with an impact factor &#40;IF&#41; are indexed there&#46; In fact&#44; other research papers similar to the present one have previously chosen only PubMed as the source to evaluate retractions&#46;<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;10&#44;11&#44;14&#44;16&#8211;18</span></a> As previously described&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> the search strategy was the following&#58; &#40;&#8220;retracted publication&#8221;&#91;Publication Type&#93; OR &#8220;retracted publication&#8221;&#91;All Fields&#93;&#41; AND &#40;&#8220;2013&#47;01&#47;01&#8221;&#91;PDAT&#93;&#58; &#8220;2016&#47;12&#47;31&#8221;&#91;PDAT&#93;&#41;&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Data extraction</span><p id="par0025" class="elsevierStylePara elsevierViewall">For each retracted article identified&#44; title&#44; author&#47;s&#44; journal name&#44; date of publication and date of retraction were obtained&#46; The time to retraction was calculated as time elapsed between both dates&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Web of Science was used to determine the Journal Citation Report &#40;JCR&#41; category&#44; 5-year impact factor &#40;5-IF&#41; and the quartile in the category&#46; Impact factor from year of publication or nearest year available was reflected&#46; Journals without 5-IF were left blank&#46; The subject category and&#44; if documented&#44; the contact information for the corresponding author&#39;s institution were recorded&#46; For journals belonging to more than one category&#44; the one corresponding to the highest quartile was selected&#46; In the case of a tie&#44; the first category in order of appearance was considered&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Definition of cause of retraction</span><p id="par0035" class="elsevierStylePara elsevierViewall">Retracted publications were classified based on retraction notice narrative and on the categories proposed by the Committee of Publishing Ethics definitions and previous classifications&#44;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">19</span></a> and were the same as in a previous paper&#46;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> Nine main categories were used&#58; aspects related with data&#44; authors issues&#44; plagiarism&#44; unethical research&#44; journal issues&#44; review process&#44; conflict of interest&#44; other&#44; and unknown&#46;<a class="elsevierStyleCrossRefs" href="#bib0165"><span class="elsevierStyleSup">4&#44;19</span></a> These categories were further classified as misconduct &#40;fraud&#41;&#44; suspicion of misconduct and no misconduct suspicion&#46; Reason for retraction was manually identified from the retraction note&#46; If more than one reason was present&#44; reason was assigned hierarchically&#44; such that manuscripts were assigned to the first reason in the list&#46; Data collection and classification were performed by ICV&#44; and doubtful assignments were discussed with ARR&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Data preparation and analysis</span><p id="par0040" class="elsevierStylePara elsevierViewall">The percentages of total retracted publications and misconduct per 10&#44;000 PubMed registries over time were calculated by dividing the total number of retracted publications due to misconduct by the total number of registries in PubMed for the study period&#46; Quartile category was categorized as high quartile &#40;quartiles 1 and 2&#41; and low quartile &#40;quartiles 3 and 4&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Differences between categorical variables were assessed by Chi-square test or Fisher&#39;s exact test&#46; Continuous variables were compared using Mann-Whitney test&#46; Non-parametric trend test analysis of variance by ranks was used to test for differences over time&#46; STATA&#47;SE&#174; v13 &#40;College Station&#44; Texas&#41; was used for all statistical analyses&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Results</span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Ratio of retraction&#44; journal quartile and JCR categories of retracted articles</span><p id="par0050" class="elsevierStylePara elsevierViewall">For the study period&#44; the total number of retracted publications was 1&#44;082 out of a total of 4&#44;384&#44;945&#44; representing a proportion of 2&#46;5 per 10&#44;000 publications&#46; Six hundred and eleven different biomedical journals retracted papers&#46; The distribution by quartile is shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; Median 5-IF was 2&#46;63 &#40;interquartile range &#91;IQR&#93;&#58; 1&#46;74-4&#46;24&#41;&#46; Of the retracted papers&#44; 51&#46;4&#37; were published in high quartile journals&#44; 33&#46;1&#37; in low quartile journals&#44; and 15&#46;5&#37; were published in journals without IF &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46; Retracted papers were mainly of the biochemistry and molecular biology areas &#40;9&#46;9&#37;&#41;&#44; followed by oncology &#40;7&#46;1&#37;&#41; &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Annual evolution&#44; median time to retraction and reasons for retraction</span><p id="par0055" class="elsevierStylePara elsevierViewall">Despite no significant trend was detected &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;9&#41;&#44; the crude number of retractions has increased over time&#44; with 70 retractions &#40;6&#46;4&#37;&#41; in 2013 and 418 &#40;38&#46;6&#37;&#41; in 2016&#46; Plagiarism has steadily increased with only 35 papers retracted for that reason in 2013 &#40;9&#46;9&#37;&#41; and 161 in 2016 &#40;45&#46;5&#37;&#41;&#46; Plagiarism was also the main cause of retraction in 2016&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">Median time to retraction was 10&#46;0 months &#40;IQR&#58; 5&#46;0-17&#46;0&#41;&#46; Time to retraction was similar between articles published in high and low quartile journals &#40;median time to retraction was of 10&#46;0 months &#91;IQR&#58; 5&#46;0-19&#46;0&#93; for the former and 10&#46;0 months &#91;IQR&#58; 5&#46;0-17&#46;5&#93; for the latter&#41;&#46; There was no difference in time to retraction regarding the specific reason for retraction &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;2&#41;&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Presence of misconduct among retracted papers</span><p id="par0065" class="elsevierStylePara elsevierViewall">Definitive misconduct was found in 707 &#40;65&#46;3&#37;&#41; of all retracted papers&#46; Additionally&#44; proportion of misconduct among retracted papers or reason for retraction did not change over time &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;2&#41;&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Within the retracted publications&#44; among low-impact journals the presence of misconduct was higher with a 73&#37; compared to 61&#37; for the high-impact journals &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">There was a significant trend to a longer time to retraction for papers retracted because of misconduct compared to those papers not retracted due to misconduct &#40;11 months &#91;IQR&#58; 5&#46;9-18&#46;0&#93; vs&#46; 5&#46;9 months &#91;IQR&#58; 2&#46;0-14&#46;0&#93;&#59; p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">There were differences in the percentage of retractions due to misconduct regarding the JCR category&#46; 91&#37; of retracted papers were due to misconduct for pathology journals and 48&#37; for pharmacology and pharmacy journals&#44; &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>&#41;&#46; It can be observed that there are important differences for the burden of misconduct among retracted papers between JCR categories&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">Among the papers retracted because of misconduct&#44; plagiarism was the main reason for retraction&#44; independently of the journal IF &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&#41;&#46; Data manipulation was the second cause of retraction among those papers retracted in high impact journals&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Of all retractions&#44; only 16 &#40;1&#46;5&#37;&#44; all because of misconduct&#41; clearly stated that the journal contacted authors and&#47;or institutions in order to communicate the retraction and the misconduct&#46;</p></span></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Discussion</span><p id="par0095" class="elsevierStylePara elsevierViewall">We present here a description of retractions broken down by journals&#8217; IF&#46; We have found that&#44; of the retracted manuscripts&#44; 51&#46;4&#37; belong to high-impact journals and that it seems that misconduct among retracted papers has apparently a higher presence in low-quartile journals&#46; The most frequent cause of misconduct is plagiarism&#44; accounting for 38&#37; of all retractions in 2016&#46; Finally&#44; only 1&#46;5&#37; of retractions were marked as having triggered an action by journals&#44; a very low percentage&#46; We do not have data on the percentage of journals contacting authors when there is a retraction and if there are differences on the frequency of this contact regarding the journal&#39;s IF&#46; However&#44; and despite no clear data were available&#44; different implications for authors have been previously described following retractions&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">20</span></a> Similarly&#44; some journals decide to penalize authors by preventing them from publishing in the journal for a period of time&#46;<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">8&#44;21</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">Fang et al&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">1</span></a> have shown in a study including papers retracted until 2012 that the mean time to retraction was 32&#46;9 months&#44; which is more than three times longer that the time observed in the present study&#46; We might speculate that this finding served editors to speed up fraud investigation when there is a suspicion and&#44; as a consequence&#44; the time to retraction has been shortened&#46; The same group has also shown that time to retraction because of fraud is longer than when retractions were due to other reasons&#46; This result is in agreement with our finding of a longer time to retraction because of misconduct&#46; This might be related to the difficulty to ensure the facts and to confirm the fraudulent conduct&#46; Also&#44; when retraction is due to reasons other than misconduct&#44; authors might be involved in the process of retraction&#44; and that seems to be a factor related with reduced time to retraction&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Journal IF also has an influence in retraction with a higher proportion of misconduct among retracted papers published in low-impact journals&#46; Previously&#44; the contrary has been shown&#44; suggesting that the greater visibility of high-impact journals promotes higher inspection and a quicker retraction&#46; We have also found that 51&#46;4&#37; of the retracted papers were published in high-quartile journals&#46; It is noteworthy that in high-impact journals&#44; a significant proportion of the misconduct is related to data manipulation by authors&#44; suggesting that high IF might be more attractive as these publications are generally linked to improvements in CVs&#44; grant success&#44; and better job opportunities&#46; This might provide some incentive to commit misconduct to publish in a high-ranking journal even though IF and quantitative measurement of publications has been largely questioned&#46;<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">16&#44;22&#44;23</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">Plagiarism accounts for the highest number of retractions for the study period&#46; These data are striking and deserve to be commented given that we have reasons to think that the real number of authors plagiarizing is higher&#46; The use of plagiarism detection software has become more widespread&#46; Despite the fact that the use of these systems prevents having plagiarized published manuscripts&#44; retractions due to plagiarism are increasing by year&#46; It is worth to mention that plagiarism was the main reason for retraction independently of the journal impact&#44; indicating that the implementation of plagiarism detection systems are in great need&#44; independently of the journal&#46; However&#44; these systems have probably prevented finding a significant increase&#46; Hence&#44; and despite awareness of editors&#44; reviewers and readers who undoubtedly are contributing to this increase in detection and retraction&#44; more action has to be done&#46;<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">8&#44;24&#44;25</span></a> However&#44; efforts to limit this phenomenon have to start from the very moment when a manuscript arrives to a medical journal and is assigned to an editor&#46; Detection of plagiarism can be done in three ways&#46; First&#44; detection can rely on the capacity of reviewers and editors to identify previously published papers&#46; Second&#44; it can use plagiarism detection software including that for image fraud detection&#46;<a class="elsevierStyleCrossRefs" href="#bib0265"><span class="elsevierStyleSup">24&#44;25</span></a> And finally&#44; detection can occur when a reader or the author is capable of identifying the plagiarism from an already published paper&#46; This method seems to be the only way to identify plagiarism when the original publication is in a language other than English and is not published in a widely visible journal&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">26</span></a> Actions other than warning authors are needed&#44; such as those in based in education&#46; It has already been tested that warnings against plagiarism are insufficient&#46;<a class="elsevierStyleCrossRefs" href="#bib0280"><span class="elsevierStyleSup">27&#44;28</span></a> There is also a lack of standardization and clarity on retraction management&#44; and databases should provide tools and procedures to trace the retractions and authors committing misconduct&#46;<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">29</span></a></p><p id="par0115" class="elsevierStylePara elsevierViewall">It is worth to mention&#44; that the entire editorial process is not paid&#44; nor valued&#44; and that in general there is not any specific training for the work&#46; Also&#44; the editorial process is based on good faith and goodwill&#46; Consequently&#44; to ask Editors and reviewers an excessive amount of work and to be fully aware of new ways of committing fraud might not be realistic&#46; Some tasks using plagiarism detection using commercial software should be done by biomedical journals&#8217; administrative staff before allowing the manuscript to enter in the editorial process&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Biochemistry and molecular biology and pathology journals are&#44; respectively&#44; the JCR categories with a greater number of retractions&#44; and with the highest proportion of misconduct among retracted papers&#44; though we do not know the total number of published papers within those categories&#46; Despite retractions and misconduct are widespread&#44; this basic discipline accounts for the greater proportion of retractions&#46; Before&#44; non-association was found between a general medicine journal &#40;vs&#46; other&#41; and misconduct&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">13</span></a> In general terms&#44; we believe that the threat of retraction and misconduct is everywhere&#44; and all journals have to be aware of it and implement measures to limit it&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">The main limitation of our study results from the fact that we are only evaluating retractions that have been identified after being published&#44; and we do not address all the plagiarism detected by the journals including any other fraud avoided by early identification during the editorial process affecting rejected papers&#46; Also&#44; as has been previously acknowledged&#44;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">15</span></a> the ability to classify publications as misconduct or not is limited and some data are not accessible&#44; such as quartile of all the publications of the study period&#46; Also&#44; we cannot evaluate the percentage of journals contacting authors and&#47;or institutions when there is a retraction&#44; and if this is related to the journal&#39;s IF&#46; The dynamic nature of data obliges us to be cautious&#46; An additional limitation is that PubMed was the only database consulted to gather the reported data&#44; though we need to take into account the fact that&#44; for medical literature&#44; Medline is the main database&#44; and where the vast majority of journals are indexed&#46; PubMed is also the database where a reader would notice if an article has been retracted&#46; Finally&#44; and perhaps most important&#44; we do not know the total number of papers published in the analysed journals and therefore we cannot infer that the incidence of retractions is higher in low-impact biomedical journals compared to high impact journals&#46; We only can conclude that the crude number of retractions &#40;and also retractions due to misconduct&#41; is higher in low impact journals</p><p id="par0130" class="elsevierStylePara elsevierViewall">To conclude&#44; retraction of scientific publications is associated with both high and low-impact journals&#44; with plagiarism as the main reason of misconduct&#44; independently of the journal IF&#46; It would be recommendable for journals to implement the use of plagiarism detection systems and to standardize measures both before and after the publication of the manuscript&#46; We encourage journal editors detecting misconduct to promote actions beyond those limited to the journal&#46;<elsevierMultimedia ident="tb0005"></elsevierMultimedia></p></span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">Editor in charge</span><p id="par0145" class="elsevierStylePara elsevierViewall">Carlos &#193;lvarez-Dardet&#46;</p></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Transparency declaration</span><p id="par0150" class="elsevierStylePara elsevierViewall">The corresponding author on behalf of the other authors guarantee the accuracy&#44; transparency and honesty of the data and information contained in the study&#44; that no relevant information has been omitted and that all discrepancies between authors have been adequately resolved and described&#46;</p></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0140">Authorship contributions</span><p id="par0155" class="elsevierStylePara elsevierViewall">I&#46; Campos-Varela and A&#46; Ruano-Ravi&#241;a wrote the manuscript and R&#46; Villaverde-Casta&#241;eda critically edited and reviewed the manuscript&#46; All authors provided critical input to the manuscript&#39;s content and have approved the final version&#46; The corresponding author attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted&#46;</p></span><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0145">Funding</span><p id="par0160" class="elsevierStylePara elsevierViewall">None&#46;</p></span><span id="sec0090" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0150">Conflicts of interest</span><p id="par0165" class="elsevierStylePara elsevierViewall">None&#46;</p></span></span>"
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              "titulo" => "Ratio of retraction&#44; journal quartile and JCR categories of retracted articles"
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              "titulo" => "Annual evolution&#44; median time to retraction and reasons for retraction"
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            1 => "Impact factor"
            2 => "Peer review"
            3 => "Plagiarism"
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            1 => "Factor de impacto"
            2 => "Revisi&#243;n por pares"
            3 => "Plagio"
            4 => "Sistemas de detecci&#243;n de plagio"
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        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To describe the biomedical journal characteristics that are associated with the retraction of papers&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A descriptive cross-sectional study was conducted&#46; All papers retracted and indexed in PubMed from January 1<span class="elsevierStyleSup">st</span> 2013 to December 31<span class="elsevierStyleSup">st</span>&#44; 2016 were included&#46; We used nine main categories to classify retractions&#58; aspects related with data&#44; authors issues&#44; plagiarism&#44; unethical research&#44; journal issues&#44; review process&#44; conflict of interest&#44; other&#44; and unknown&#46; These categories were further classified as&#58; misconduct&#44; suspicion of misconduct&#44; or no misconduct&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The proportion of retraction was 2&#46;5 per 10&#44;000 publications&#46; Retractions appeared in 611 journals&#46; During the study period&#44; retraction due to misconduct was more frequent among journals with low-impact factor&#46; Within these retracted publications&#44; among low-impact journals the presence of misconduct was higher with a 73&#37; compared to 61&#37; for the high-impact journals &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleMonospace">0</span>&#46;001&#41;&#46; There were differences in the percentage of retractions due to misconduct regarding the journal classification category &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleMonospace">0</span>&#46;001&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Retraction of publications is present in both high- and low-impact factor biomedical journals&#44; but misconduct is more frequent among the papers retracted from lower impact journals&#46; Measures before and after publication should be taken to limit misconduct&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Describir qu&#233; caracter&#237;sticas de las revistas cient&#237;ficas biom&#233;dicas se asocian con la retractaci&#243;n de art&#237;culos&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un estudio transversal en el que se incluyeron todos los art&#237;culos retractados e indexados en PubMed del 1 de enero de 2013 al 31 de diciembre de 2016&#46; Las retractaciones tambi&#233;n se clasificaron de forma m&#225;s detallada&#58; problemas con los datos o manejo de datos&#59; aspectos de autor&#237;a&#59; plagio&#59; investigaci&#243;n no &#233;tica&#59; aspectos relacionados con la revista&#59; problemas con el proceso de revisi&#243;n&#59; conflicto de intereses o razones desconocidas&#46; Posteriormente se clasificaron como mala conducta&#44; sospecha de mala conducta o sin mala conducta&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">La proporci&#243;n de retractaciones fue de 2&#44;5 por cada 10&#46;000 publicaciones&#46; Hubo retractaciones en 611 revistas&#46; Durante el periodo de estudio&#44; la retractaci&#243;n por mala conducta fue m&#225;s frecuente en revistas con bajo factor de impacto&#44; y entre los art&#237;culos retractados&#44; hubo m&#225;s mala conducta &#40;73&#37;&#41; entre las revistas de bajo factor de impacto&#44; en comparaci&#243;n con las revistas con alto factor de impacto &#40;61&#37;&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Tambi&#233;n se observan diferencias en el porcentaje de retractaciones debidas a mala conducta seg&#250;n la categor&#237;a de clasificaci&#243;n del Journal Citation Report &#40;p &#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La retractaci&#243;n de publicaciones est&#225; presente tanto en revistas de alto como de bajo factor de impacto&#44; pero la retractaci&#243;n por mala conducta es m&#225;s habitual en revistas biom&#233;dicas de bajo impacto&#46; Deben tomarse medidas antes y despu&#233;s de la publicaci&#243;n para limitar la mala conducta cient&#237;fica&#46;</p></span>"
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">119 &#40;11&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>No impact factor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">168 &#40;15&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2377093.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Distribution of retracted journals by quartile&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Only reported categories with a proportion of retractions greater than 3&#37;&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Retractions&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Biochemistry &#38; Molecular Biology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">107 &#40;9&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Oncology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">77 &#40;7&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mutidisciplinay Sciences&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">62 &#40;5&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medicine&#44; Research &#38; Experimental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45 &#40;4&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pathology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">36 &#40;3&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Biotechnology &#38; Applied Microbiology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">35 &#40;3&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medicine&#44; General &#38; Internal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">33 &#40;3&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pharmacology &#38; Pharmacy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">33 &#40;3&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2377095.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Distribution of retracted journals by Journal Citation Report category&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Included only articles with known quartile&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">High quartile&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Low quartile&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Misconduct</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Yes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">339 &#40;61&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">261 &#40;72&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26 &#40;4&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14 &#40;3&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Uncertain&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">191 &#40;34&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">83 &#40;23&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2377096.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Distribution of misconduct by quartile&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0020"
        "etiqueta" => "Table 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at4"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Misconduct&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pathology&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">33 &#40;91&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medicine&#44; General &#38; Internal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26 &#40;78&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Oncology&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
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          "en" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Presence of misconduct by Journal Citation Report category&#46;</p>"
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          "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">What is known about the topic&#63;</span><p id="par0135" class="elsevierStylePara elsevierViewall">Scientific misconduct is a relevant problem in scientific publication&#46; There is little knowledge on the burden of misconduct within retracted papers by biomedical journals and the misconduct characteristics when it is present&#46; Furthermore&#44; there is scarce information regarding retractions and misconduct broken down by journals&#8217; impact factor and Journal Citation Report categories&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">What does this study add to the literature&#63;</span><p id="par0140" class="elsevierStylePara elsevierViewall">Retraction and misconduct in publications is present in both high- and low-impact factor journals&#44; but misconduct is more frequent among papers retracted in lower impact journals&#46; There are also differences on the presence of misconduct between journal&#39;s classification categories&#46; More in-depth research is needed to know misconduct related differences between journals&#8217; characteristics&#46;</p></span></span>"
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Article information
ISSN: 02139111
Original language: English
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